Search results for "Formal Comment"

showing 3 items of 3 documents

openSNP–A Crowdsourced Web Resource for Personal Genomics

2014

Genome-Wide Association Studies are widely used to correlate phenotypic traits with genetic variants. These studies usually compare the genetic variation between two groups to single out certain Single Nucleotide Polymorphisms (SNPs) that are linked to a phenotypic variation in one of the groups. However, it is necessary to have a large enough sample size to find statistically significant correlations. Direct-To-Consumer (DTC) genetic testing can supply additional data: DTC-companies offer the analysis of a large amount of SNPs for an individual at low cost without the need to consult a physician or geneticist. Over 100,000 people have already been genotyped through Direct-To-Consumer genet…

GenotypeScienceInformation Storage and RetrievalBiological Data ManagementGenome-wide association studyGenomicsBiologySocial and Behavioral SciencesPolymorphism Single NucleotideFormal CommentGenomic MedicineGenome Analysis Toolsddc:570Genetic variationGenome-Wide Association StudiesGenome DatabasesGeneticsmedicineHumansGenetic TestingPrecision MedicineBiologyGenetic Association StudiesInformation ScienceGenetic testingGenetic associationClinical GeneticsGeneticsInternetMultidisciplinarymedicine.diagnostic_testInformation DisseminationQPersonalized MedicineRComputational BiologyHuman GeneticsGenomicsGeneticistData scienceOpen dataPhenotypeGenetics of DiseaseMedicineCrowdsourcingSoftwareResearch ArticleGenome-Wide Association StudyPersonal genomicsPLoS ONE
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Dinosaur Metabolism and the Allometry of Maximum Growth Rate

2016

In his 2016 paper, Myhrvold criticized ours from 2014 on maximum growth rates (Gmax, maximum gain in body mass observed within a time unit throughout an individual’s ontogeny) and thermoregulation strategies (ectothermy, endothermy) of 17 dinosaurs. In our paper, we showed that Gmax values of similar-sized extant ectothermic and endothermic vertebrates overlap. This strongly questions a correct assignment of a thermoregulation strategy to a dinosaur only based on its Gmax and (adult) body mass (M). Contrary, Gmax separated similar-sized extant reptiles and birds (Sauropsida) and Gmax values of our studied dinosaurs were similar to those seen in extant similar-sized (if necessary scaled-up) …

0106 biological sciences0301 basic medicineMetabolic stateMetabolic AnalysisPhysiologylcsh:MedicineAnimal Phylogenetics01 natural sciencesBody TemperatureDinosaursMathematical and Statistical TechniquesExtant taxonMedicine and Health SciencesBody SizeGrowth ratelcsh:Sciencemedia_commonArchosauriaData ManagementMammalsMultidisciplinaryEcologyFossilsEukaryotaRegression analysisPrehistoric AnimalshumanitiesCurve FittingPhylogeneticsBioassays and Physiological AnalysisPhysiological ParametersEctothermPhysical SciencesVertebratesRegression AnalysisStatistics (Mathematics)Research ArticleComputer and Information Sciencesmedia_common.quotation_subjectVertebrate PaleontologyBiologyResearch and Analysis Methods010603 evolutionary biologyMarsupialsFormal CommentBirds03 medical and health sciencesBasal Metabolic Rate MeasurementAnimalsEvolutionary SystematicsStatistical MethodsPaleozoologyTaxonomyEvolutionary BiologyVariableslcsh:ROrganismsReptilesBiology and Life SciencesPaleontology030104 developmental biologyEvolutionary biologyBasal metabolic rateAmniotesEarth Scienceslcsh:QAllometryPaleobiologyEnergy MetabolismZoologyMathematical FunctionsMathematicsPLoS ONE
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Response to formal comment on Myhrvold (2016) submitted by Griebeler and Werner (2017)

2018

In his 2016 paper, Myhrvold criticized ours from 2014 on maximum growth rates (Gmax, maximum gain in body mass observed within a time unit throughout an individual’s ontogeny) and thermoregulation strategies (ectothermy, endothermy) of 17 dinosaurs. In our paper, we showed that Gmax values of similar-sized extant ectothermic and endothermic vertebrates overlap. This strongly questions a correct assignment of a thermoregulation strategy to a dinosaur only based on its Gmax and (adult) body mass (M). Contrary, Gmax separated similar-sized extant reptiles and birds (Sauropsida) and Gmax values of our studied dinosaurs were similar to those seen in extant similar-sized (if necessary scaled-up) …

0106 biological sciences0301 basic medicineMetabolic AnalysisPhysiologylcsh:MedicineAnimal Phylogenetics01 natural sciencesDinosaursBody TemperatureExtant taxonOrnithologyMaximum gainMedicine and Health SciencesGrowth rateSauropsidalcsh:ScienceArchosauriaData ManagementMammalsMultidisciplinarybiologyVertebrateEukaryotaPrehistoric AnimalsThermoregulationPhylogeneticsBioassays and Physiological AnalysisPhysiological ParametersEctothermVertebratesRegression AnalysisComputer and Information SciencesVertebrate PaleontologyZoologyResearch and Analysis Methods010603 evolutionary biologyFormal CommentBirds03 medical and health sciencesbiology.animalBasal Metabolic Rate MeasurementAnimalsAnimal PhysiologyEvolutionary SystematicsPaleozoologyTaxonomyEvolutionary Biologylcsh:ROrganismsBiology and Life SciencesPaleontologyReptilesbiology.organism_classificationBird Physiology030104 developmental biologyAmniotesEarth Scienceslcsh:QAllometryPaleobiologyZoologyPLoS ONE
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